We develop new biophysical methods to understand how molecular machines edit and repair our genomes. Current lab interests include CRISPR-cas adaptive immunity and eukaryotic DNA repair.

December 19, 2025: Selma, Hongshan, and Eric’s One-Pot isothermal CRISPR detection paper is published in ACS Synthetic Biology.

November 19, 2025: IJF is quoted in Popular Mechanics on DNA data storage — “All of Humanity’s Knowledge Could Become Immortal Inside a Tiny Device.” (Text,PDF)

October 28, 2025: Jesse Buffington is awarded an NIH F31 Ruth L. Kirschstein Predoctoral Fellowship.

October 23, 2025: Jesse, Jami, Kuang, You-Chiun, and Kamyab’s retron genome editing paper is published in Nature Biotechnology. Our work is written up in CNS News (Text,PDF), SciTechDaily (Text,PDF), and ScienceDaily (Text,PDF).

September 13, 2025: Alvin, Selma, Jami, Carlos, and Daphne post their Cas13d structure preprint on bioRxiv, revealing the structural basis for target discrimination and activation.

Published 19 Dec 2025
Published 23 Oct 2025
Published 19 Jul 2025
Published 22 Apr 2025