XPD helicase speeds through a molecular traffic jam.

Ilya J. Finkelstein and Eric C. Greene, Mol Cell 35 (5) :549-50 (2009).


Helicases and other DNA translocases must travel along crowded substrates. In this issue, Honda et al. (2009) report that the archaeal XPD helicase can bypass a single-stranded DNA-binding protein without either molecule being ejected from the DNA.